Both sides make four changes following their Champions League exploits in midweek.
Aston Villa boss Unai Emery restores Johan Manzambi to the starting line-up, with Matty Cash, Ian Maatsen and Boubacar Kamara also coming in.
Emiliano Buendia, Tyrone Mings, Ross Barkley and Ibrahim Mbaye make way.
Aston Villa XI: Suzuki, Cash, Lindelof, Torres, Maatsen, McGinn, Kamara, Gomes, Alysson, Manzambi, Jackson.
The big team news for Manchester City sees the return to the starting line-up for star striker Erling Haaland, who was on the bench against AEK Athens.
Iliman Ndiaye, Jeremy Doku and Marc Guehi all come in to the starting line-up.
Tuesday’s hat-trick hero Phil Foden, Floyd Samba, Allan and Rico Lewis make way.
Man City XI: Donnarumma, Khusanov, Dias, Guehi, Gvardiol, Anderson, Fernandez, Ndiaye, Doku, Cherki, Haaland.
